At the core of the power struggle among states key to Middle Eastern stability and global balance is the question of who controls whose natural gas flow via whose territories. The United States, Russia, Turkey, Syria, and Iran are analyzed in this context to present how changing alliances have disrupted the regional balance in the Syria conflict. Given the stable hostility between the United States and Russia as well as the steady friendship between Russia and Syria, Turkey’s alliances and enmities are central in the formation of balances. Competition or disagreement between the United States and Russia over Kurdish independence in Syria could lead to a protracted conflict for years to come in the Middle East.